Related Gene(s): BAP1, EPCAM*, FH, FLCN, MET, MITF, MLH1, MSH2, MSH6, PMS2, PTEN, SDHA, SDHB, SDHC, SDHD, TP53, TSC1, TSC2, VHL
Next generation sequencing (NGS) is used to offer a comprehensive hereditary kidney cancer panel. Genes on this panel include: BAP1, EPCAM, FH, FLCN, MET, MITF, MLH1, MSH2, MSH6, PMS2, PTEN, SDHA, SDHB, SDHC, SDHD, TP53, TSC1, TSC2, and VHL. Full gene sequencing is performed for 18 of the genes (excluding EPCAM). For MITF, only the status of the c.952G>A (p.E318K) alteration is analyzed and reported. Gross deletion/duplication analysis is performed for 18 genes (excluding MITF). Specific Site Analysis is available for individual gene mutations identified in a family.
This test will be available soon. For additional information, please contact us.