Related Gene(s): BRCA1, BRCA2, CDH1, PALB2, PTEN, TP53
BRCAplus is a next generation sequencing panel of 6 genes associated with breast cancer (BRCA1, BRCA2, CDH1, PALB2, PTEN, and TP53). These six genes are associated with five hereditary cancer syndromes (hereditary breast and ovarian cancer or HBOC, hereditary diffuse gastric cancer, hereditary breast and pancreatic cancer, Cowden syndrome, and Li-Fraumeni syndrome), all of which have published management guidelines. Identification of a mutation in one of these genes can help estimate cancer risk and guide treatment, screening, and/or prevention decisions for the patient. Family members can be tested for a familial mutation to determine if they have high risk (positive for the familial mutation) or average risk (negative for the familial mutation) for cancer.
This test will be available soon. For additional information, please contact us.