Results you can trust

Sema4 Natalis was developed by a team of leading clinical and molecular geneticists, pediatricians, and scientists with expertise in pediatric genetic conditions. This test was carefully designed to provide results that are both accurate and useful, based on years of research and clinical experience in molecular diagnostics. Sema4 Natalis met strict criteria, including

Analytic validity, or how accurately a test can detect a certain genetic change (or variant). All DNA samples for Sema4 Natalis are analyzed in our CLIA-certified lab using advanced DNA sequencing technology that is >95% accurate
Clinical validity, or how well a genetic test can predict a certain disease. Sema4 Natalis only screens for genetic changes that are highly penetrant. This means that if someone is born with genetic change(s) screened for by this test, there is a high probability (>80%) that they will develop symptoms of the associated disease
Clinical utility, or whether a genetic test provides useful information that can help improve treatment choices or other healthcare decisions. Sema4 Natalis only screens for conditions that can be treated* with medication, dietary modification, or other therapies

You can learn more about how to evaluate the quality of a genetic test through Genetics Home Reference, a website from the U.S. National Library of Medicine.

Always consult with your child’s pediatrician before taking any medical action or starting treatment based on results of screening with Sema4 Natalis.